Ilisiakos put on an impressive second-half display to beat the visitors 84-74 and give their survival hopes a real boost.
Ilisiakos now have 15 points, one less than Iraklis, AEK and Panellinios.
In the day's other game, Panionios beat fellow strugglers AEK 78-75.
However, the win was overshadowed by a serious injury to the home side's Milos Vujanic in the second half.
The Serb suffered a broken leg, which means that his move to Partizan Belgrade has been scuppered.
The game against AEK was due to be the guard's last for Panionios.
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